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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DYNC2H1 All Species: 28.18
Human Site: Y4272 Identified Species: 62
UniProt: Q8NCM8 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8NCM8 NP_001073932 4307 492594 Y4272 E C I S L P V Y T S A E R D R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536596 4306 491933 Y4271 E C I S L P V Y T S A E R D R
Cat Felis silvestris
Mouse Mus musculus Q45VK7 4306 492321 Y4271 E C I S L P V Y T S A E R E R
Rat Rattus norvegicus Q9JJ79 4306 492200 Y4271 E C I S L P V Y T S A E R D C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509757 4391 500194 Y4356 E C I S L P V Y T S A E R E Q
Chicken Gallus gallus XP_417173 4301 491979 Y4266 E C I S L P V Y T S M E R D R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P37276 4639 530166 N4602 L T L P V Y L N S T R T E L L
Honey Bee Apis mellifera XP_395108 4023 452032 Y3987 D I V N I P V Y V N S Q R D E
Nematode Worm Caenorhab. elegans Q19542 4171 473799 S4140 Q I Q V P V Y S S S E R S D L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36022 4092 471329 Y4073 P R E S I L N Y E R L Q A K E
Red Bread Mold Neurospora crassa P45443 4367 495560 V4349 L I G N L K K V T D L L D E G
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.5 N.A. 93.3 93 N.A. 85.8 79.7 N.A. N.A. N.A. 26.4 30.3 40.7 N.A.
Protein Similarity: 100 N.A. N.A. 96.5 N.A. 97.1 97 N.A. 91.8 89.4 N.A. N.A. N.A. 47.8 52.5 61.2 N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 93.3 93.3 N.A. 86.6 93.3 N.A. N.A. N.A. 0 33.3 13.3 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 93.3 N.A. 100 93.3 N.A. N.A. N.A. 33.3 80 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.8 27.6
Protein Similarity: N.A. N.A. N.A. N.A. 44.3 48.2
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 46 0 10 0 0 % A
% Cys: 0 55 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 10 0 0 0 0 0 0 0 0 10 0 0 10 55 0 % D
% Glu: 55 0 10 0 0 0 0 0 10 0 10 55 10 28 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 28 55 0 19 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 10 0 0 0 0 0 0 10 0 % K
% Leu: 19 0 10 0 64 10 10 0 0 0 19 10 0 10 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 19 0 0 10 10 0 10 0 0 0 0 0 % N
% Pro: 10 0 0 10 10 64 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 10 0 0 0 0 0 0 0 0 19 0 0 10 % Q
% Arg: 0 10 0 0 0 0 0 0 0 10 10 10 64 0 37 % R
% Ser: 0 0 0 64 0 0 0 10 19 64 10 0 10 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 64 10 0 10 0 0 0 % T
% Val: 0 0 10 10 10 10 64 10 10 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 73 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _